Welcome to Novo Nordisk in the United States

Hormone Therapy



We manufacture and sell two market leading hormone therapy products: Activella and Vagifem. Both products have been available in the U.S. since mid-2000 and Novo Nordisk is excited to offer the lowest vaginal estrogen commercially available.

Vagifem ® is approved in the U.S. for the treatment of atrophic vaginitis resulting from estrogen deficiency. Vagifem is a tablet containing natural estrogen, which is administered intravaginally by a disposable applicator. We have established a toll-free number for women and their healthcare providers to call for further information regarding the availability of Vagifem: 

1-888-VAGIFEM (1-888-824-4336)


Activella®, packaged in a 28-day calendar dial, is a low dose continuous-combined once-daily tablet combining estrogen and progestin for the treatment of moderate to severe vasomotor symptoms associated with menopause, the treatment of vulvar and vaginal atrophy, and the prevention of postmenopausal osteoporosis in women with an intact uterus. Novo Nordisk has established a toll-free number for women and their healthcare providers to call for further information regarding the availability of Activella:  

1-866-NOVO-FEM (1-866-668-6336)