Welcome to Novo Nordisk in the United States


Diabetes

Novo Nordisk offers products that help treat type 1 or type 2 diabetes at various stages of the disease’s progression. The chart below highlights when certain medications should be considered for diabetes management. As with all medications, it’s important to take your medicine as instructed.

And remember, diabetes control also involves following good diet and exercise habits.

Victoza®
(liraglutide [rDNA origin] injection)
 

Victoza® (liraglutide [rDNA origin] injection) is a non-insulin medicine that–along with diet and exercise–can help control type 2 diabetes. It helps lower blood sugar in as soon as 2 weeks–and helps keep it down. Victoza® works like a natural hormone in your body called GLP-1 to help lower blood sugar when it is high. It comes in a prefilled pen and is taken once-a-day, anytime of day, with or without meals. While not a weight-loss product, Victoza® may help you lose some weight.
www.victoza.com

Click here for Important Safety Information
Please click here for Victoza® Prescribing Information, including Medication Guide.

Levemir®
(insulin detemir [rDNA origin] injection)
 

Levemir® (insulin detemir [rDNA origin] injection) is a long-acting insulin that can help control high blood sugar in adults with type 1 or type 2 diabetes and children with type 1 diabetes for up to 24 hours and is covered by most health insurance plans. Levemir® is the only long-acting insulin analog approved by the FDA for use with pregnant women as well as children with type 1 diabetes as young as 2 years of age. Levemir® is available in FlexPen®, a discreet, prefilled, dial-a-dose insulin pen and is covered by most health insurance plans. For more information and money saving offers, please visit the website listed below.
www.levemir.com

Click here for Important Safety Information
Click here for Levemir® Prescribing Information

NovoLog®
(insulin aspart [rDNA origin] injection)
 

NovoLog® (insulin aspart [rDNA origin] injection) is a fast-acting mealtime insulin that helps control blood sugar when taken with long acting insulin and has helped millions of people with type 1 and type 2 diabetes since 2001. Because type 2 diabetes changes over time, consider adding NovoLog® when you eat for the additional control you need. NovoLog® is available in FlexPen®, a discreet, prefilled, dial-a-dose insulin pen and is covered by most health insurance plans. Ask your doctor if fast-acting NovoLog® is right for you. For more information and money saving offers, please visit the website listed below.
www.novolog.com

Click here for Important Safety Information
Click here for Novolog® Prescribing Information

NovoLog® Mix 70/30
(70% insulin aspart protamine suspension
and 30% insulin aspart injection, [rDNA origin])
 

NovoLog® Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin]) is a man-made insulin which provides benefits at mealtime as well as between meals. NovoLog® Mix 70/30 is available in Flexpen, a discreet, prefilled, dial-a-dose insulin pen. For more information, visit the website listed below.
http://www.novologmix70-30.com

Click here for Important Safety Information
Click here for Novolog® Mix 70/30 Prescribing Information

Prandin®
(repaglinide)
 

Prandin® (repaglinide) is an oral blood sugar-lowering drug used in the management of type 2 diabetes.
www.prandin.com

Click here for Important Safety Information
Click here for Prandin® Prescribing Information

GlucaGen® HypoKit®
(glucagon [rDNA origin] for injection)
 

GlucaGen® HypoKit® (glucagon [rDNA origin] for injection) is Novo Nordisk's emergency kit for the treatment of very low blood sugar. It contains an injection of glucagon, a hormone that raises your blood sugar level.
More information about GlucaGen® HypoKit®

Click here for Important Safety Information
Click here for GlucaGen® HypoKit® Prescribing Information

Important Safety Information for All Diabetes Products

Victoza®Back to Top

Indications and Usage:
Victoza® (liraglutide [rDNA origin] injection) is an injectable prescription medicine that may improve blood sugar (glucose) in adults with type 2 diabetes when used along with diet and exercise.

Victoza® is not recommended as the first medication to treat diabetes. Victoza® has not been studied in patients with history of inflammation of the pancreas (pancreatitis). Victoza® is not a substitute for insulin and has not been studied in combination with prandial (mealtime) insulin. Victoza® is not for people with type 1 diabetes or people with diabetic ketoacidosis. It is not known if Victoza® is safe and effective in children. Victoza® is not recommended for use in children.

Important Safety Information:
In animal studies, Victoza® caused thyroid tumors - including thyroid cancer - in some rats and mice. It is not known whether Victoza® causes thyroid tumors or a type of thyroid cancer called medullary thyroid cancer (MTC) in people, which may be fatal if not detected and treated early. Do not use Victoza® if you or any of your family members have a history of MTC or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). While taking Victoza®, tell your doctor if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer.

Do not use Victoza® if you are allergic to liraglutide or any of the ingredients in Victoza®. Serious allergic reactions can happen with Victoza®. If symptoms of serious allergic reactions occur, stop taking Victoza® and seek medical attention. Pancreatitis may be severe and lead to death. Before taking Victoza®, tell your doctor if you have had pancreatitis, gallstones, a history of alcoholism, or high blood triglyceride levels since these medical conditions make you more likely to get pancreatitis.

Stop taking Victoza® and call your doctor right away if you have pain in your stomach area that is severe and will not go away, occurs with or without vomiting, or is felt going from your stomach area through to your back. These may be symptoms of pancreatitis.

Before using Victoza®, tell your doctor about all the medicines you take, especially sulfonylurea medicines or insulin, as taking them with Victoza® may affect how each medicine works. If you use Victoza® with insulin, you may give both injections in the same body area (for example, your stomach area), but not right next to each other.

Also tell your doctor if you have severe stomach problems such as slowed emptying of your stomach (gastroparesis) or problems with digesting food; have or have had kidney or liver problems; have any other medical conditions; or are pregnant or plan to become pregnant. Tell your doctor if you are breastfeeding or plan to breastfeed. It is unknown if Victoza® will harm your unborn baby or if Victoza® passes into your breast milk.

Your risk for getting hypoglycemia, or low blood sugar, is higher if you take Victoza® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. The dose of your sulfonylurea medicine or insulin may need to be lowered while taking Victoza®.

Victoza® may cause nausea, vomiting, or diarrhea leading to dehydration, which may cause kidney failure. This can happen in people who have never had kidney problems before. Drinking plenty of fluids may reduce your chance of dehydration.

The most common side effects with Victoza® incluade headache, nausea, and diarrhea. Nausea is most common when first starting Victoza®, but decreases over time in most people. Immune system related reactions, including hives, were more common in people treated with Victoza® compared to people treated with other diabetes drugs in medical studies.

Please click here for Victoza® Prescribing Information.
Victoza® is a prescription medicine.


Levemir®Back to Top

What is Levemir® (insulin detemir [rDNA origin] injection)?

  • Levemir® is a man-made insulin used to control high blood sugar in adults and children with diabetes mellitus.
  • Levemir® is not meant for use to treat diabetic ketoacidosis.

Important Safety Information:
Who should not take Levemir®?
Do not take Levemir® if:

  • you have an allergy to Levemir® or any of the ingredients in Levemir®.
Before taking Levemir®, tell your health care provider about all your medical conditions including, if you are:
  • pregnant, plan to become pregnant, or are breastfeeding.
  • taking new prescription or over-the-counter medicines, including supplements.

Talk to your health care provider about how to manage low blood sugar.

How should I take Levemir®?

  • Read the Instructions for Use and take exactly as directed.
  • Know the type and strength of your insulin. Do not change your insulin type unless your health care provider tells you to.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them.
  • Do not share needles, insulin pens, or syringes. You may give or get an infection from another person.
  • Never inject Levemir® into a vein or muscle.
What should I avoid while taking Levemir®?
  • Do not drive or operate heavy machinery, until you know how it affects you.
  • Do not drink alcohol or use medicines that contain alcohol.
What are the possible side effects of Levemir®?
Serious side effects can lead to death, including:
Low blood sugar. Some signs and symptoms include:
  • anxiety, irritability, mood changes, dizziness, sweating, confusion, and headache.

Your insulin dose may need to change because of:

  • change in level of physical activity, weight gain or loss, increased stress, illness, or change in diet.

Other common side effects may include:

  • reactions at the injection site, itching, rash, serious allergic reactions (whole body reactions), skin thickening or pits at the injection site (lipodystrophy), weight gain, swelling of your hands and feet and if taken with thiazolidinediones (TZDs) possible heart failure.

Get emergency medical help if you have:

  • trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.
Please click here for Levemir® Prescribing Information.
Levemir® is a prescription medicine.




NovoLog®Back to Top

Indications and Usage
What is NovoLog® (insulin aspart [rDNA origin] injection)?

  • NovoLog® is a man-made insulin used to control high blood sugar in adults and children with diabetes mellitus.

Important Safety Information:
Who should not use NovoLog®?
Do not take NovoLog® if:

  • your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients.
Before taking NovoLog®, tell your health care provider about all your medical conditions including, if you are:
  • pregnant, plan to become pregnant, or are breastfeeding.
  • taking new prescription or over-the-counter medicines, including supplements.

Talk to your health care provider about how to manage low blood sugar.

How should I take NovoLog®?

  • Read the Instructions for Use and take exactly as directed.
  • NovoLog® is fast-acting. Eat a meal within 5 to 10 minutes after taking it.
  • Know the type and strength of your insulin. Do not change your insulin type unless your health care provider tells you to.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them.
  • Do not share needles, insulin pens, or syringes. You may give or get an infection from another person.
What should I avoid while taking NovoLog®?
  • Do not drive or operate heavy machinery, until you know how NovoLog® affects you.
  • Do not drink alcohol or use medicines that contain alcohol.

What are the possible side effects of NovoLog®?
Serious side effects can lead to death, including:
Low blood sugar. Some signs and symptoms include:

  • anxiety, irritability, mood changes, dizziness, sweating, confusion, and headache.

Your insulin dose may need to change because of:

  • weight gain or loss, increased stress, illness, or change in diet or level of physical activity.

Other common side effects may include:

  • low potassium in your blood, injection site reactions, itching, rash, serious whole body allergic reactions, skin thickening or pits at the injection site, weight gain, and swelling of your hands and feet.

Get emergency medical help if you have:

  • trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.

Please click here NovoLog® Prescribing Information.
NovoLog® is a prescription medication.




NovoLog® Mix 70/30®Back to Top

Indications and Usage
What is NovoLog® Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin])?

  • NovoLog® Mix 70/30 is a man-made insulin used to control high blood sugar in adults with diabetes mellitus.
  • It is not known if NovoLog® Mix 70/30 is safe or effective in children.

Important Safety Information:
Who should not use NovoLog® Mix 70/30?

  • Do not use NovoLog® Mix 70/30 if your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients.
What should I tell my healthcare provider before taking NovoLog® Mix 70/30?
  • About all of your medical conditions, including liver, kidney, or heart problems.
  • If you are pregnant, breastfeeding, or plan to do either.
  • About all prescription and nonprescription medicines you take, including supplements, as your dose may need to change.
How should I take NovoLog® Mix 70/30?
  • NovoLog® Mix 70/30 starts acting fast. If you have type 1 diabetes, inject within 15 minutes before you eat a meal. If you have type 2 diabetes, inject within 15 minutes before or after starting your meal.
  • Inject NovoLog® Mix 70/30 under the skin of your stomach area, upper
    arms, buttocks, or thighs, but never into a vein or muscle.
  • Do not mix NovoLog® Mix 70/30 with other insulin products or use in an insulin pump.
  • Do not change your dose or type of insulin unless you are told to by your health care provider.
  • Do not share needles, insulin pens, or syringes.
  • Check your blood sugar levels as directed by your health care provider.
What should I consider while using NovoLog® Mix 70/30?
  • Alcohol, including beer and wine, may affect your blood sugar.
  • Be careful when driving a car or operating machinery. You may have difficulty concentrating or reacting if you have low blood sugar. Talk to your health care provider if you often have low blood sugar or no warning signs of low blood sugar.
What are the possible side effects of NovoLog® Mix 70/30?
  • Low blood sugar, including when too much is taken. Some symptoms include sweating, shakiness, confusion, and headache. Severe low blood sugar can cause unconsciousness, seizures, and death.
  • Serious allergic reactions may occur. Get medical help right away, if you develop a rash over your whole body, have trouble breathing, a fastheartbeat, or sweating.
  • Other side effects include low potassium in your blood, injection site reactions (like redness, swelling, and itching), skin thickening or pits at the injection site, weight gain, swelling of your hands and feet, if taken with thiazolidinediones (TZDs) possible heart failure, and vision changes.
Please click here for NovoLog® Mix 70/30 Prescribing Information.
NovoLog® Mix 70/30 is a prescription medication.




Prandin®Back to Top

Indications and Usage:
Prandin® (repaglinide) tablets are used in addition to diet and exercise to control blood sugar levels in adults with type 2 diabetes.

Important Safety Information:
Do not take Prandin® if you have diabetic ketoacidosis (a complication of diabetes resulting in a buildup of ketones [a by-product of fat breakdown] in the body) with or without coma, type 1 diabetes or are allergic to Prandin® or any of its ingredients. Prandin® should not be used if you are also taking NPH insulin. Do not take Prandin® if you take a prescription medication called gemfibrozil. Hypoglycemia (low blood sugar) is possible in people taking Prandin®. Mild to moderate cases of hypoglycemia occurred in 16% of patients taking Prandin® alone.

In one-year clinical studies in patients taking only Prandin®, the most common side effects leading to discontinuation of Prandin® were hyperglycemia (high blood sugar), hypoglycemia, and related symptoms. The most common other side effects reported form other studies comparing Prandin® to placebo or other diabetes medicines were cold- and flu-like symptoms, headache, sinusitis, nausea, diarrhea, joint ache, and back pain. In trials comparing Prandin® to another class of diabetes medications called sulfonylureas, serious heart-related side effects, including ischemia (decreased blood flow to the heart), were higher with Prandin® (4% compared to 3%). In 1 year long controlled studies, treatment with Prandin® was not associated with an increased risk of death when compared to other diabetes medicines taken by mouth.

In clinical studies comparing Prandin® to another class of diabetes medications called thiazolidinediones (TZD), hypoglycemia occurred in 7% of patients taking both drugs, 7% of patients taking Prandin® alone, and 2% of patients taking only TZD. The percentage of patients having fluid retention in the extremities per 24 weeks of treatment was 5% for patients taking both Prandin® and a TZD and 4% for patients taking only a TZD. No fluid retention in the extremities was reported in patients taking Prandin® alone. Two patients, both with a history of heart blood vessel disease, reported fluid retention with heart failure; no cases with patients taking either drug alone were reported. The average change in weight in patients taking Prandin® and a TZD was +4.9 kilograms.


Please click here for Prandin® Prescribing Information.
Prandin® is a prescription medication.




GlucaGen® Hypokit®Back to Top

Indications and Usage:
GlucaGen® (glucagon [rDNA origin] for injection) is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) that can happen in people who have diabetes and use insulin. Symptoms of severe hypoglycemia include confusion, loss of consciousness, and seizures. You should only give GlucaGen® injection if (1) the person is unconscious or (2) the person is having a seizure or (3) the person is confused and unable to eat sugar or a sugar-sweetened product. Less severe cases of hypoglycemia should be treated right away by eating sugar or a sugar sweetened product such as a regular soft drink or fruit juice. GlucaGen® does not work if it is taken by mouth.

Important Safety Information:
Do not use GlucaGen® if you are allergic to glucagon or lactose, have a tumor of the adrenal gland called a pheochromocytoma, or have a tumor of the pancreas called insulinoma.

Hypoglycemia may happen again after receiving GlucaGen® treatment. You must be given a fast-acting source of sugar followed by a long-acting source of sugar by mouth as soon as you are awake and able to swallow.

Tell your doctor about all medicines you take and all of your medical conditions, including if you are pregnant or breastfeeding. GlucaGen® may affect the way other medicines work, and other medicines may affect how GlucaGen® works.

GlucaGen® may cause serious side effects including allergic reactions. Symptoms of a severe allergic reaction may include rash or itching, raised red patches on your skin (hives), swelling of the face, lips, tongue or throat, problems breathing or swallowing, very high or very low blood pressure, or fast or slow heart beat. The most common side effects of GlucaGen® include nausea and vomiting.


Please click here for GlucaGen® Hypokit Prescribing Information.
GlucaGen® Hypokit is a prescription medication.

Talk to your doctor about the importance of diet and exercise in your treatment plan.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Novo Nordisk provides patient assistance for those who qualify. Please call 1-866-310-7549 to learn more about Novo Nordisk assistance programs.

Selected Important Safety Information for Victoza®

In animal studies, Victoza® caused thyroid tumors—including thyroid cancer—in some rats and mice. It is not known whether Victoza® causes thyroid tumors or a type of thyroid cancer called medullary thyroid cancer (MTC) in people, which may be fatal if not detected and treated early. Do not use Victoza® if you or any of your family members have a history of MTC or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). While taking Victoza®, tell your doctor if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer.

Selected Important Safety Information for Levemir®, NovoLog®, NovoLog® Mix 70/30®

What should I tell my health care provider before taking Levemir®, NovoLog®, or NovoLog® Mix 70/30?
  • About all of your medical conditions.
  • If you are pregnant, plan to become pregnant, or are breastfeeding.
  • About all prescription and over-the-counter medicines you take, including supplements.
Talk to your health care provider about how to manage low blood sugar. How should I take Levemir®, NovoLog®, or NovoLog® Mix 70/30?
  • Read the Instructions for Use and take exactly as directed.
  • Take Levemir®, NovoLog®, or NovoLog® Mix 70/30 as directed by your health care provider. Do not change your dose or type of insulin unless you are told to by your health care provider.
  • Check your blood sugar levels as directed by your health care provider.
  • Do not share needles, insulin pens, or syringes. You may give or get an infection from another person.
What are some possible side effects of Levemir®, NovoLog®, and NovoLog® Mix 70/30? Serious side effects can lead to death, including:
  • Low blood sugar, including when too much is taken. Some symptoms include anxiety, irritability, mood changes, dizziness, sweating, confusion, and headache.
Get emergency medical help if you have:
  • trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.